Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review

Current Knowledge and Perspectives of Pyrrolizidine Alkaloids in Pharmacological Applications: A Mini-Review

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Pyrrolizidine alkaloids (PAs) are a widespread group of secondary metabolites in plants.PAs are notorious for their acute Outdoor End Table hepatotoxicity, genotoxicity and neurological damage to humans and animals.In recent decades, the application of PAs for beneficial biological activities to cure disease has drawn greater attention.Here, we review the Unframed Entertainment Photos current knowledge regarding the pharmacological properties of PAs and discuss PAs as promising prototypes for the development of new drugs.